James L Cook Selected Research

Fibrochondrogenesis

1/2014	Culture of equine fibroblast-like synoviocytes on synthetic tissue scaffolds towards meniscal tissue engineering: a preliminary cell-seeding study.
4/2011	Evaluation of in vitro growth factor treatments on fibrochondrogenesis by synovial membrane cells from osteoarthritic and nonosteoarthritic joints of dogs.

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James L Cook Research Topics

Disease

25	Osteoarthritis 01/2022 - 10/2002
14	Pain (Aches) 06/2022 - 04/2016
13	Infections 08/2022 - 06/2004
12	Neoplasms (Cancer) 07/2021 - 07/2002
8	Inflammation (Inflammations) 04/2021 - 01/2003
7	Wounds and Injuries (Trauma) 01/2020 - 06/2008
4	Arthritis (Polyarthritis) 09/2014 - 10/2004
3	Intervertebral Disc Degeneration 01/2022 - 12/2020
3	Rupture 07/2021 - 07/2014
3	Anterior Cruciate Ligament Injuries 05/2017 - 10/2015
2	Postoperative Pain 06/2022 - 07/2020
2	Surgical Wound Infection 03/2022 - 09/2021
2	Knee Injuries (Knee Injury) 01/2022 - 09/2021
2	Synovitis 07/2021 - 10/2007
2	Hypertrophy 01/2020 - 09/2003
2	Persistent Infection 01/2019 - 01/2018
2	Hip Dislocation 01/2019 - 10/2005
2	Knee Osteoarthritis 10/2016 - 04/2016
2	Osteosarcoma (Osteogenic Sarcoma) 08/2016 - 09/2003
2	Sepsis (Septicemia) 04/2016 - 02/2008
2	Fibrochondrogenesis 01/2014 - 04/2011
1	Arthralgia (Joint Pain) 01/2022
1	Weight Loss (Weight Reduction) 12/2021
1	Disease Progression 12/2021
1	Bone Resorption 12/2021
1	Closed Fractures (Closed Fracture) 09/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 07/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 07/2021
1	Hypothyroidism 07/2021
1	Hypertension (High Blood Pressure) 07/2021
1	Peripheral Vascular Diseases (Peripheral Vascular Disease) 07/2021
1	Rotator Cuff Tear Arthropathy 07/2021
1	Soft Tissue Infections 07/2021
1	Spinal Cord Injuries (Spinal Cord Injury) 04/2021
1	Edema (Dropsy) 04/2021
1	Plague (Bubonic Plague) 12/2020
1	Breakthrough Pain 09/2020
1	Bone Fractures (Bone Fracture) 09/2020
1	Rotator Cuff Injuries 08/2020
1	Body Weight (Weight, Body) 01/2020

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2002
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2011
6	Biological ProductsIBA 01/2022 - 07/2002
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 07/2002
4	Anti-Bacterial Agents (Antibiotics)IBA 07/2021 - 02/2008
4	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 04/2021 - 10/2016
4	CytokinesIBA 01/2020 - 03/2014
4	Matrix Metalloproteinases (MMPs)IBA 01/2019 - 09/2002
4	salicylhydroxamic acid (SHAM)IBA 10/2016 - 12/2008
4	Hyaluronic Acid (Hyaluronan)IBA 10/2016 - 10/2002
3	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 10/2004 - 09/2002
2	Narcotics (Narcotic Analgesics)IBA 06/2022 - 01/2022
2	Pharmaceutical PreparationsIBA 01/2022 - 06/2004
2	Ibuprofen (Motrin)FDA LinkGeneric 04/2021 - 09/2020
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020 - 10/2002
2	Virulence Factors (Pathogenicity Factors)IBA 01/2018 - 05/2011
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018 - 04/2003
2	Serum Amyloid A Protein (Serum Amyloid A)IBA 03/2013 - 10/2004
2	EnzymesIBA 02/2008 - 10/2004
1	AcidsIBA 08/2022
1	SolutionsIBA 06/2022
1	Interleukin-8 (Interleukin 8)IBA 01/2022
1	Interleukin-10 (Interleukin 10)IBA 01/2022
1	Caffeine (No Doz)FDA LinkGeneric 01/2022
1	KetorolacIBA 01/2022
1	Tissue Inhibitor of Metalloproteinase-1IBA 01/2022
1	Interleukin-6 (Interleukin 6)IBA 01/2022
1	Morphine (MS Contin)FDA LinkGeneric 01/2022
1	Ropivacaine (Naropin)FDA LinkGeneric 01/2022
1	Epinephrine (Adrenaline)FDA LinkGeneric 01/2022
1	Interleukin-18 (Interleukin 18)IBA 01/2022
1	Bacterial DNAIBA 09/2021
1	Dichlorodiphenyldichloroethane (DDD)IBA 07/2021
1	HemosiderinIBA 07/2021
1	Indomethacin (Indometacin)FDA LinkGeneric 04/2021
1	Oxycodone (Oxycontin)FDA LinkGeneric 09/2020
1	Opioid Analgesics (Opioids)IBA 07/2020
1	ChemokinesIBA 01/2020

Therapy/Procedure

6	Therapeutics 09/2021 - 09/2003
5	Transplantation 06/2022 - 01/2021
4	Debridement 08/2022 - 07/2009
4	Knee Replacement Arthroplasty (Total Knee Replacement) 12/2021 - 12/2015
3	Replacement Arthroplasty 09/2021 - 10/2017
3	Osteotomy 09/2021 - 10/2005
3	Arthroplasty 09/2021 - 07/2020
3	Aftercare (After-Treatment) 01/2020 - 10/2009
3	Intra-Articular Injections 10/2016 - 10/2007
2	Operative Surgical Procedures 06/2022 - 12/2015
2	Pain Management 09/2020 - 07/2020
2	Sutures (Suture) 10/2019 - 03/2007
2	Autologous Transplantation 04/2016 - 06/2008
2	Drug Therapy (Chemotherapy) 05/2005 - 06/2003
1	Anterior Cruciate Ligament Reconstruction 01/2022
1	Bariatric Surgery 12/2021
1	Physical Therapy Modalities (Physical Therapy Technique) 09/2021
1	Durable Medical Equipment (Medical Equipment, Durable) 09/2021
1	Catheters 07/2021
1	Braces 12/2020
1	Blood Flow Restriction Therapy 01/2020
1	Resistance Training 01/2020